Antioxidant (Superoxide and Hydroxyl Radical Scavenging), Antidiabetic Potential and Bioactive Chemical Properties of Celery (Apium graveolens)

Celery plant, which is also called Apium graveolens Linn, is an Asian plant that belongs to the family of Apiaceae. It can also be used to make many other things that include oil, fresh herbs, seeds and stalks, used in cooking and medicine. Phytochemical studies revealed the presence of numerous phytochemicals including, steroids, flavonoids in addition to vitamins A and C. The essential oils, leaves and seeds of the plant are used in traditional medicine. The paper aimed to discuss bioactive chemical properties and antioxidant activity of celery (Apium graveolens) and its use as an antidiabetic. The compounds present in the methanol extract identified by GC-mass analysis were 1-Pyrenehexadecanoicacid, Cyclohexanol, t-Butyltrifluoroacetate D-Ascorbic acid, 7Z,10Z-hexadecadienoic acid, N-Methyl-N-benzyltetradecanamine, oleic acid, 1-(trifluoromethyl) Cyclopropanemethanol, n-Hexadecanoic acid methyl ester, Butyric acid, 2-tridecyl ester, Butyric acid, 2-tridecyl ester, Phytol oleate, 9,12-Octadecadienoic acid, and cinnamaldehyde. The crude methanolic extract, ethyl acetate fraction, ethanol fraction, and celery (Apium graveolens) standards all demonstrated antioxidant potential, specifically in terms of superoxide radical scavenging, with values of (153.00±4.71, 109.45±5.53, 181.00±6.80, and 572.19±19.00, respectively). The results of hydroxyl radical scavenging were obtained as follows: (21.08±1.04, 27.00±1.46, 25.65±1.40 Quercetin (standard), and 572.19±19.00 respectively). The greatest dose that was studied produced the strongest inhibition, whereas the lowest amount produced the weakest. The inhibitory potency against α-amylase was measured to be (87.01±4.06, 31.00±2.05, 49.68±2.75, and 16.00±1.03) according to the kind of celery extract (Crude methanolic extract), ethyl acetate fraction, ethanol fraction, and acarbose (Standard), respectively. α-Glucosidase activity was measured as follows: (61.94±3.07, 42.81±2.15, 30.45±2.03, and 07.96±0.65, respectively).