Antioxidant (Singlet Oxygen Scavenging and Hypochlorous Acid Scavenging) and Screening of Bioactive Chemical Compounds of Hollyhock (Alcea Rosea L.) by GCMS Method
10.52845/CMRO/2026/9-2-8
Abstract
As a rich source of phytochemicals i.e. flavonoids and phenolics, Alcea rosea (also referred to as Hollyhock) is a potent antioxidant. The high concentration of antioxidants present in Alcea rosea (Hollyhock) can be used to treat coughs, skin complications and possibly to cure disorders such as diabetes, since this plant contains high levels of antioxidants such as phenolic compounds and flavonoids that can be utilized to treat oxidative stress, inflammation and boosting the immune system. Extracts of the plant tested in laboratories were very active and compared to vitamin C in terms of radical scavenging and preventing cell damage. This study identified the following secondary metabolites, 3-Oxabicyclo [3.1.0] hexane-2, 4-dione, 1-Methylcyclohexa-1, 3-diene, Nonadecanedioic acid, hexadecanoic acid, thiosulfuric acid, 6-tetramethylbicyclo- [2.2.2] oct-2-ene, N-acetyl-4- nitrophenylhydroxylamine hydrobromide, benzen Antioxidant activity, that is, scavenging hypochlorous acid and singlet oxygen, of methanolic crude extract and ethanol fraction of the plant hollyhock ( Alcea Rosea L.) has been determined. Some of the extracts that were recorded to possess Singlet oxygen scavenging activity included methanolic crude extract, ethanol fraction, and standard (695.00±34.09, 537.83±22.71, and 748.00±26.04 respectively). The ascorbic acid (standard) 501.06±29.14, and the hypochlorous acid scavenging (286.05±25.37) were reported respectively.
Keywords
- Antioxidant
- Bioactive
- Compounds
- Alcea Rosea L.
- GCMS
How to Cite
Taisir Ali O., Sarah R. Saleh, Zahraa A. Al-Ajeeli , Noor Adnan Neama . (2026). Antioxidant (Singlet Oxygen Scavenging and Hypochlorous Acid Scavenging) and Screening of Bioactive Chemical Compounds of Hollyhock (Alcea Rosea L.) by GCMS Method. Journal of Current Medical Research and Opinion , Vol. 9 No. 02 (2026) , 4649-4656 . https://doi.org/10.52845/CMRO/2026/9-2-8