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In Vitro Antibacterial Activity of Cinnamomum zeylanicum and Screening of Its Bioactive Compounds

Published 2025-10-29 Issue Vol. 8 No. 10 (2025) Pages 4477-4485 Section Original Research
DOI 10.52845/CMRO/2025/8-10-4
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Abstract

Background: Cinnamomum zeylanicum is a plant containing antimicrobial properties in the extracts. It is the presence of compounds like cinnamaldehyde that makes it possess an antibacterial effect and it does act as such to bacteria.

Materials and Methods: Cinnamon sticks of Cinnamomum zeylanicum were dried and ground in a mortar and pestle at room temperature level. Three cold extractions (25 0 C) and 72 hours were carried out to macerate the plant samples in order to obtain ethanol extracts of 80% (v/v) concentration. Extraction of volatile bioactive chemicals through GC-MS. GC is then employed to determine the component constituents of the essential oils and the molecular mass of those constituents is determined by subsidizing Mass Spectrometry (MS) using fragmentation.

Results: The components of findings were fifteen in the case of C. zeylanicum following a GC-MS analysis. These are; 9,12-octadecadienoic acid (Z,Z)-, Cinnamic alcohol, PALmitic acid vinyl ester, Caryophyllene, Trans -2-decenal, Eugenol, D-limonene, Hexadecanoic acid, ethyl ester, 6-Methyl-5-hepten-2-one, Benzaldehyde, Cinnamic aldehyde, Phenyl ethyl acetate and 6-Methyl-5-hepten Enterococcus faecalis (26.09±0.43) was demonstrated to have a strong efficacy on the metabolites of Cinnamomum zeylanicum.

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Keywords

  • Antibacterial Activity
  • Bioactive Compounds
  • Cinnamomum zeylanicum
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How to Cite

Al-Zubaidi Sura . (2025). In Vitro Antibacterial Activity of Cinnamomum zeylanicum and Screening of Its Bioactive Compounds. Journal of Current Medical Research and Opinion , Vol. 8 No. 10 (2025) , 4477-4485 . https://doi.org/10.52845/CMRO/2025/8-10-4

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