The Analysıs of Endometrıal Samplıng on Results Reported as Insuffıcıent Samples
Insuffıcıent Endometrıal Samplıng
10.52845/CMRO/2025/8-8-4
Abstract
OBJECTIVE
The aim of this study is to evaluate the pathology results of second endometrial samplings performed in cases where the initial endometrial sampling was reported as insufficient material by the pathology unit.
MATERIAL METHOD
This study analyzed the results of 6,612 patients who underwent endometrial sampling at Prof. Dr. Cemil Taşçıoğlu City Hospital between 2019 and 2023, using the hospital's electronic record system. Data from 615 patients whose samples were reported as insufficient and 257 patients who underwent repeat procedures were included in the study. Patients were evaluated based on age, parity, menopausal status, indication for endometrial sampling, endometrial thickness, and the type of anesthesia used.
STATİSTİCAL METHOD
For statistical analysis, SPSS 15.0 for Windows was used. Descriptive statistics were presented as numbers and percentages for categorical variables, and as mean, standard deviation, minimum, maximum, and median for numerical variables. Since the assumption of normal distribution was not met, comparisons of numerical variables between more than two independent groups were performed using the Kruskal-Wallis test, while comparisons between two groups were conducted using the Mann-Whitney U test. Subgroup analyses were interpreted using Bonferroni correction. Proportions between groups were compared using the Chi-square test. A significance level of p<0.05 was considered statistically significant.
FINDINGS
The files of 6612 patients were reviewed. Pathology results of 615 (9.3%) of these patients were evaluated as inadequate specimens. According to hospital data, 257 of these 615 patients underwent repeat endometrial biopsy, 105 (40.8%) of whom had an unsatisfactory result. Of the 152 patients with an adequate sample, atrophy (34.2%), endometrial polyp (32.2%), hormonal effect (25.7%) and malignancy (7.9%) were diagnosed in the second endometrial sampling.
CONCLUSİON
The detection of malignancy in 7.9% of patients who underwent repeat sampling after an initial insufficient endometrial pathology result highlights the importance of repeating the procedure, especially in older patients. Additionally, the fact that 40.8% of repeat samplings also resulted in insufficient specimens suggests that alternative methods should be considered for second endometrial samplings.
Keywords
- Endometrial sampling
- İnsufficient samplıng
- endometrial malignancy
How to Cite
DR. Ramazan ADAN, DR. Doğaç ALTIPARMAK, DR. Sinan SÜRÜCÜ, DR. Teksin İŞGÖRÜCÜ, DR. Fatih ŞAHİN, DR. Veli MİHMANLI . (2025). The Analysıs of Endometrıal Samplıng on Results Reported as Insuffıcıent Samples: Insuffıcıent Endometrıal Samplıng. Journal of Current Medical Research and Opinion , Vol. 8 No. 8 (2025) , 4438- 4444 . https://doi.org/10.52845/CMRO/2025/8-8-4