Detection and Estimation of Some Hematological and Immunological Parameters among Patients with Intestinal Parasites in Babylon, Iraq

Background Parasitic infections caused by intestinal helminthes and protozoan parasites in humans are related with major health problem especially in the regions  with poor sanitation and bad personal hygiene. Objectives: Present study is aimed to detection of intestinal parasites and study its effects on some hematological and immunological parameters on patients

Material and methods: The study was conducted in Al- Mahaweel district-hospital, Babylon. from May to September/2022. A stool and blood samples were collected from ( 100)patients and(30) control group to detection of intestinal parasitic infections and to estimate total count of RBCs and Hb , total and differential counts of WBCs and estimate some immunological parameters like as level of   IL-5 and IgE in sera of patients and correlated with control group.

Results appear the infection rate (49%) and the infection rate rise significantly in females (64.2%) than males(29.54%) .There are many intestinal parasites were detected ,The high rate of infection with E. vermicularis (20.4%) while the lowest rate of infection with  A. duodenale(8.6%)). Hematological result reported a significant decreased in total count of RBCs and Hb of infected group (3.96× 10‘ cell /mm³) and (8.72 mg/ 100 ml ), respectively compared with control group (5. 62× 10‘ cell /mm³) and (11.87mg/ 100ml) respectively . A Significant increased were reported in total counts of WBCs of infected group (10.5 cell /mm³) as compared with control group (6.31 cell/mm³). Differential WBCs appears significant increase( p<0.05) in  eosinophils (6.22%)  in patients while no variation in number of other type of WBCs  when compared with control group. Results of immunological data reveal to a significant elevation (P < 0.05) in both IgE, and IL-5 serum level among infected group when compared with control group.