Journal of Medical Research and Health Sciences <p><a class="cmp_edit_link" href="">&nbsp;Edit<span class="pkp_screen_reader">Edit About the Journal</span></a></p> <p><strong>Journal of Medical Research and Health Sciences</strong>&nbsp; aims to improve health status and quality of care for individuals, families and communities. The Health Science Journal (1791-809X) aspires to provide the scientific knowledge through the publication of peer-reviewed, high quality, scientific papers and other material on all topics related to Biochemistry, Biotechnology, Health engineering, Epidemiology, Genetics, Nursing, Pharmacology, Pharmacy, Public health, Psychology, Physical therapy, and Medicine ensuring a rapid turn-around time possible for reviewing and publishing of articles freely for research, teaching and reference purposes.</p> <p><strong>Medical Research and Health Sciences</strong>&nbsp;is one of the most emerging fields in the present scenario. The involvement of the new discoveries and prevailing research made this ever flourishing domain of health care more advancing. The research and development in Health Science leading many new discoveries of medicines, medical equipment, psychological health advancement, etc. almost every nation in the world is more concerned of the development of this area of research to let their medical field grow in much advanced manner. The level of health science involvement in the fields of scientific research has reached to that extend; the health safety of any developing as well as developed nation can be evaluated through the level of advancement of health science of the particular nation.</p> en-US (Praveen Kottathveetil) (Daga) Fri, 08 Jun 2018 10:59:51 +0000 OJS 60 An Evaluation on Oral Vestibular Schwannoma Growth from the Viewpoint of Molecular Biology <p>This author has known Medical Hypotheses several years ago, unfortunately did not know that it is available online until lately, when he read Prof. Gong Peng’s important hypotheses. &nbsp;</p> <p>This author has been honored to receive the invitation from Prof. Ping Gong [an oral surgeon] for our potential collaborationin the near future. In the meantime, please correct some possible errors in this author’s own writing as presented below, and the possibility of applying his own concepts into the important future research.&nbsp;</p> Kasia D. mohkara ##submission.copyrightStatement## Fri, 01 Jun 2018 00:00:00 +0000 Under-Five Children Diarrheal Satus And Assocaited Factors Among Implemented And Not Implemented Community-Led Total Sanitation And Hygiene In Yaya Gulele District,Ehiopia,2017. A Community-Based Comparative Cross Sectional Study Design Triangulated With <p><strong>Purpose:</strong> The aim of this study was to assess under five diarrheal status and associated factors among implemented and not implemented Community-led total sanitation and Hygiene in Yaya Gulele woreda, Ethiopia, 2017.</p> <p><strong>Methods:</strong>&nbsp; Community-based comparative cross sectional study-involving 380 households from each implemented and not implemented community-led total sanitation and hygiene (CLTSH) area was conducted from December 1 to June 30, 2017. Pretested structured questionnaire and a complete observational checklist were used to collect data. Qualitative data were collected via focus group discussions and analyzed manually. Data were checked and entered to Epi info 3.5.4 and analyzed by SPSS version 20. Bivariate and multivariable logistic regression analyses were computed</p> <p><strong>Results:</strong>&nbsp; In this study,of the households of participants , 88% inimplemnted and 66% in not implemented Community-Led Total Sanitation and Hygiene (CLTSH) had latrine. Of latrine owned households, 85% in implemented &nbsp;and 75% in not implemented CLTSH utilize latrine properly. In the study area, 12% in implemented and 34% in not implemented CLTSH area practice open defecation.</p> <p>Two weeks period diarrhea prevalence was13.4% (95%CI: 10.2-17.3%) in implemented CLTSH and 36.3% (95%CI: 31.7-41.6%) in not implemented CLTSH were reported. Two and above under five years old children [AOR= 2.33;95% CI (1.09-4.96)], not clean water storage [AOR=2.36; 95%CI (1.16-4.80)], negative attitude of mothers/caregivers towards diarrhea [AOR=2.07; 95%CI (1.06-4.04)], presence of feces in the compound [AOR=1.88;95%CI (1.10-3.22)] and lack of hand washing facility in the compound [AOR=2.64; 95%CI (1.47-4.74)] were associated factors of &nbsp;the outcome. <strong>Conclusions:</strong> implementation of CLTSH is the applicable tool to reduce diarrhea prevalence.Having more than two under five years old children,not clean water storage,negative attitude of mothers towards of diarrhea,existence of feces in the compound and lack of handwashing facility in the compound were associated factors to under five years old diarrheal status.. Health workers and local authorities inspire the community to clean water storage and the environment,to change mothers’ behaviour towards diarrhea as well as construct handwashing facility in the compound.</p> Zerihun Degebasa, Dawit zenebe, Taklu Marama ##submission.copyrightStatement## Fri, 01 Jun 2018 00:00:00 +0000 Secretion Levels of Some Endogenous Antimicrobial Peptides and Cytokines in Type 2 Diabetes Mellitus <p>The article presents data on the level of secretion of endogenous antimicrobial peptides and cytokines in type 2 diabetes mellitus.</p> <p>Aim. To assess the secretion levels of antimicrobial peptides (defensin and endotoxin) and cytokines (interleukin-8, tumor necrosis factor α and transforming growth factor β<sub>1</sub>) in blood plasma in type 2 diabetes mellitus.</p> <p>Methods<strong>.</strong> Blood samples of 87 patients with type 2 diabetes mellitus were examined. All patients were assigned to three groups depending on blood glucose and glycosylated hemoglobin levels: compensation – 36 subjects, subcompensation – 34 subjects, decompensation – 17 patients. ELISA test was used to measure the levels of cytokines («Bender Medsystems» kits, Austria) and antimicrobial peptides (set «Hycult Biotech»).</p> <p>Results. In the first group (compensation stage), defensin level was 17.6% higher than in the control group. The second group (subcompensation) showed a 4-fold increase in defensin level, while in the third group (decompensation stage) there was a 14.4-fold increase, compared to the control. Endotoxin concentration was 1.18 ± 0.05 ng/ml in the first group, 1.57 ± 0.14 ng/ml in the second group, and 18.2 ± 0.09 for the third group, where the control value was 0.33 ± 0.12 ng/ml.</p> <p><strong>Conclusion. </strong>An association was revealed between the secretion of antimicrobial peptides and cytokines. Concentration of antimicrobial peptides and cytokines reflects the stage of type 2 diabetes mellitus.</p> Efendiyev A. M, 1Azizova G. I., 1Dadashova A. R., Topchiyeva Sh.A. ##submission.copyrightStatement## Fri, 01 Jun 2018 00:00:00 +0000 Does the practice of the European Court of Human Rights have any legal implications on the development of cross-border surrogacy? <p><strong>Medical tourism</strong> is the area of tourism, the aim of which is to organize the treatment of citizens abroad. Medical tourism appeared relatively recently, but already established itself as one of the most popular types of tourism. It combines several areas: recreation; health improvement; therapy etc. According to G. Pennings, ,, In recent years the term ‘<strong>reproductive tourism</strong>’ has been increasingly used to refer to couples travelling from their country of residence to another in order to receive specific infertility treatment not allowed or not available in their own country&nbsp;“.<a href="#_ftn1" name="_ftnref1">[1]</a> The cross-border or international surrogacy is the kind of reproductive tourism. It means that ,,the patients have the purpose of going around the restrictions and bans their national legislation has set down in the country of origin and obtaining care not avalaible to them domestically. This is often a direct consequence of restrictive legislation in domestic countries, and as such needs to be dealt with by their domestic legislation”.<a href="#_ftn2" name="_ftnref2">[2]</a> International or cross-border surrogacy (also referred as reproductive tourism) is a contract between potential parents and a surrogate mother abroad. In most cases, they are commercial in nature. That is to say, women are paid for their services. Many countries ban paid surrogacy. Others allow for reasonable medical expenses to be paid. Nineteen states of the USA have laws recognizing compensated surrogacy. Some scholars argue that India and Ukraine are two of the most popular destinations for commercial surrogacy.<a href="#_ftn3" name="_ftnref3">[3]</a></p> <p>&nbsp;</p> Chakhvadze B.I., Chakhvadze G.B., Fedotova E.V. ##submission.copyrightStatement## Fri, 01 Jun 2018 00:00:00 +0000